Where we are
Via Pietro Castellino 111
80131 Naples
Tel. 0039 081 6132 579
Links
Amministrazione trasparente
Marinella Pirozzi
Current Position:
Researcher
Contacts:
Cell Physiology Lab
Member of the Euro-bioimaging Facility
Phone: +39 0816132544
Lab: +39 0816132713
Email: marinella.pirozzi@cnr.it
m.pirozzi@ieos.cnr.it
Keywords:
Light and electron microscopy, Correlative microscopy (CLEM), Live imaging, Cell BiologyMarinella Pirozzi, as a microscopy specialist provides all of the Institute investigators with the latest imaging technologies, such as wide-field, fluorescence and confocal microscopy, live imaging, image acquisition, digital image analysis as basic and advanced applications (deconvolution, 3D rendering), and the expertise of using these tools. She provides technical assistance for the use of optical basic and advanced light microscopy instrumentations; provides consultation and training to use the various techniques of light and fluorescence microscopy, image analysis and processing and data transfer and storage; performs independent and collaborative preparations and analysis of specimens for electron microscopy. She has expertise in the realization of the services of the Facility, for the planning process and experiments, for the control and for the evaluation of the results; organization of the imaging service carried out for researchers by managing requests for access to the Facility, identifying their priorities and feasibility; management of the Facility's imaging equipment; coordination, direction and execution of the experimental application in the choice of tools and methodologies to achieve the objectives of the service and responsibility for their achievement; care of relations with users; resolution of any service management problems and proposals for corrective measures.
2014-present Researcher at National Research Council – Institute Experimental Endocrinology and Oncology "Gaetano Salvatore" – Second Unit (IEOS-SS), Naples, Italy
2007-2014 Staff Responsible of TIGEM Microscopy and Imaging Core, Telethon Institute of Genetic and Medicine, Naples.
2001-2006 Post-doc position at TIGEM, Telethon Institute of Genetic and Medicine, Naples.
2002 PhD in Biochemistry and Molecular Biology. University of Naples “Federico II”.
1996 Master Degree in Biological Sciences, with 110/110 cum laude with a dissertation in Biochemistry, University of Naples “Federico II”.
1991-1996. Student in Biological Sciences. University of Naples “Federico II”, Naples, Italy.
Grimaldi G, Filograna A, Schembri L, Lo Monte M, Di Martino R, Pirozzi M, Spano D, Beccari AR, Parashuraman S, Luini A, Valente C, Corda D. PKD-dependent PARP12-catalyzed mono-ADP-ribosylation of Golgin-97 is required for E-cadherin transport from Golgi to plasma membrane. Proc Natl Acad Sci USA. Jan 4;119(1) (2022). PMID: 34969853
Pothukuchi P, Agliarulo I, Pirozzi M, Rizzo R, Russo D, Turacchio G, Nüchel J, Yang JS, Gehin C, Capolupo L, Hernandez-Corbacho MJ, Biswas A, Vanacore G, Dathan N, Nitta T, Henklein P, Thattai M, Inokuchi JI, Hsu VW, Plomann M, Obeid LM, Hannun YA, Luini A, D'Angelo G, Parashuraman S. GRASP55 regulates intra-Golgi localization of glycosylation enzymes to control glycosphingolipid biosynthesis. EMBO J., 2021 Oct 18 40(20) (2021). PMID: 34516001
Chiritoiu M, Brouwers N, Turacchio G, Pirozzi M, Malhotra V. GRASP55 and UPR control Interleukin-1b aggregation and secretion. Developmental Cell, Apr 8, 49:145–155 (2019). PMID: 30880003
Subramanian A, Capalbo A, Iyengar NR, Rizzo R, di Campli A, Lo Monte M, Beccari A, Yerudkar A, del Vecchio C, Glielmo L, Turacchio G, Pirozzi M, Kim SG, Henklein P, Cancino J, Parashuraman S, Diviani D, Fanelli F, Sallese M, Luini A. Auto-regulation of secretory flux by sensing and responding to the folded cargo protein load in the endoplasmic reticulum. CELL Mar 7; 176(6): 1461-1476 (2019). PMID: 30849374
Capasso S, Sticco L, Rizzo R, Pirozzi M, Russo D, Dathan NA, Campelo F, van Galen J, Hölttä‐Vuori M, Turacchio G, Hausser A, Malhotra V, Riezman I, Riezman H, Ikonen E, Luberto C, Parashuraman S, Luini A and D’Angelo G. Sphingolipid metabolic flow controls phosphoinositide turnover at the trans‐Golgi network. EMBO J. May 2, 36 (9): 1117–1297 (2017). PMID: 28495678
Progetto "Piattaforma Robotica di Incubazione per la Microscopia Ottica (PRIMO)" tra CNR (IEOS capofila-IGB-IBBR) e OKOLAB s.r.l. per attività di Ricerca Industriale e Sviluppo Sperimentale, da realizzare con cofinanziamento del Ministero delle Imprese e del Made in Italy (MIMIT) nell'ambito del Piano Nazionale Complementare (PNC) al PNRR, a valere sulla misura Accordi per l'innovazione di cui al D.M. 31.12.2021 e al D.D. 14.11.2022.