Maria Mangini

Current Position:
Researcher, TD
Contacts:
Biophotonics and Advanced Microscopy Lab
Phone: +39 0816132225
Lab: +39 08161322206
Email:
maria.mangini@cnr.it
m.mangini@ieos.cnr.it
Keywords:
Cell biology, Raman microscopy, Confocal imagingMy primary research is dedicated to advancing the frontier of innovative diagnostic and therapeutic tools for the early detection and treatment of cancer. To achieve these goals, I adopt a comprehensive multidisciplinary approach. Specifically, I utilize label-free imaging techniques, such as Raman micro-spectroscopy, to develop cutting-edge diagnostic tools. Concurrently, I employ biochemical and molecular biology techniques to scrutinize the impact of emerging therapies, particularly nanovectors, on the mechanisms underlying cancer.
Education:
December 2018 - PhD in Molecular Life Science at the University of Campania “Luigi Vanvitelli”
October 2013 - Master’s degree in medical biotechnologies at the University of Naples “Federico II”
October 2011 - Bachelor’s degree in health biotechnologies at the University of Naples “Federico II”
Positions
June 2023- currently Fixed-term researcher at IEOS-SS, CNR, Naples, Italy.
March 2019-June 2023 Post-doc fellow at IEOS-SS, CNR, Naples
October 2015-October 2018 PhD student at IBBC, CNR, Naples
October 2017-December 2017 Visiting PhD student at the Brigham and Women’s Hospital-Harvard Medical School, Boston (MA), USA.
Maria Mangini, Maria Antonietta Ferrara, Gianluigi Zito, Stefano Managò, Alberto Luini, Anna Chiara De Luca, Giuseppe Coppola “Cancer metabolic features allow discrimination of tumor from white blood cells by label-free multimodal optical imaging”. Frontiers in Bioengineering and Biotechnology. 2023 https://doi.org/10.3389/fbioe.2023.1057216
Maria Mangini, Rosa D’angelo, Caterina Vinciguerra, Christine Payré, Gérard Lambeau, Barbara Balestrieri, Julia F Charles, Stefania Mariggiò “Multimodal regulation of the osteoclastogenesis process by secreted group IIA phospholipase A2”. Frontiers in Cell and Developmental Biology. 2022 https://doi.org/10.3389/fcell.2022.966950
Maria Mangini, Alessandro Verde, Diana Boraschi, Victor F Puntes, Paola Italiani, Anna Chiara De Luca “Interaction of nanoparticles with endotoxin: Importance in nanosafety testing and exploitation for endotoxin binding”. Nanotoxicology. 2021 https://doi.org/10.1080/17435390.2021.1898690
Maria Giovanna Mosca, Maria Mangini, Stefania Cioffi, Pasquale Barba, Stefania Mariggiò “Peptide targeting of lysophosphatidylinositol-sensing GPR55 for osteoclastogenesis tuning”. Cell Communication and Signaling. 2021 https://doi.org/10.1186/s12964-021-00727-w
Silvia Romano, Maria Mangini, Erika Penzo, Stefano Cabrini, Anna Chiara De Luca, Ivo Rendina, Vito Mocella, Gianluigi Zito “Ultrasensitive surface refractive index imaging based on quasi-bound states in the continuum” ACS Nano 2020. https://doi.org/10.1021/acsnano.0c06050
Maria Mangini, Enrico Iaccino, Maria Giovanna Mosca, Selena Mimmi, Rosa D’Angelo, Ileana Quinto, Giuseppe Scala, Stefania Mariggiò “Peptide-guided targeting of GPR55 for anti-cancer therapy” Oncotarget. 2017 doi: 10.18632/oncotarget.14121