Where we are
Via Pietro Castellino 111
80131 Naples
Tel. 0039 081 6132 579
Links
Amministrazione trasparente
Ilenia Agliarulo
Current Position:
Researcher, TD
Contacts:
Phone: +39 0816132312
Email:
Ilenia.agliarulo@cnr.it
i.agliarulo@ieos.cnr.it
Keywords:
Cell biology, super resolution microscopy, Glycosilation, GolgiMy research aims to reveal the mechanisms governing post-translational modification in the Golgi compartment. Currently, I am focusing on the S-palmitoylation, a reversible lipid modification that affects protein localization and function. It is my goal to improve our understanding of this enzymatic reaction since there is still a lack of information on several aspects, such as the signals governing palmitoyltransferases localization. To accomplish this goal, I am using biochemical assays to determine palmitoylation of specific substrates and imaging techniques to determine the localization of substrates and palmitoylatransferases within cellular compartments.
Education:
May 2016 - PhD in Biochemistry and Cellular and Molecular Biology at University of Naples “Federico II”,
December 2012 - Master’s degree in Medical biotechnology at the University of Naples “Federico II”
March 2011 - Bachelor’s degree in Health biotechnologies at the University of Naples “Federico II”
Positions
June 2023- currently Fixed-term researcher at IEOS-SS, CNR, Naples, Italy.
April 2022-June 2023 Post-doc fellow at IEOS-SS, CNR, Naples
February 2019-March 2022 Post-doc fellow at IBBC, CNR, Naples
January 2018-December 2018 Post-doc fellow at IBP, CNR, Naples
April 2016-December 2017 Post-doc fellow at University of Naples “Federico II”
March 2015-November 2015 Visiting PhD student at the University of Pennsylvania, Dept of Chemistry, PA, USA
Rosario Avolio, Ilenia Agliarulo, Daniela Criscuolo, Daniela Sarnataro, Margherita Auriemma, Sara Pennacchio, Giovanni Calice, Martin Y. Ng, Carlotta Giorgi, Paolo Pinton, Barry Cooperman, Matteo Landriscina, Franca Esposito, and Danilo Swann Matassa “Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins” Genome Research 2023 PMID: 36712063
Danilo Swann Matassa, Daniela Criscuolo, Rosario Avolio, Ilenia Agliarulo, Daniela Sarnataro, Consiglia Pacelli, Rosella Scrima, Alessandra Colamatteo, Giuseppe Matarese, Nazzareno Capitanio, Matteo Landriscina end Franca Esposito “Regulation of mitochondrial complex III activity and assembly by TRAP1 in cancer cells” Cancer Cell International 2022 https://doi.org/10.1186/s12935-022-02788-4
Ilenia Agliarulo and Seetharaman Parashuraman “Golgi Apparatus Regulates Plasma Membrane Composition and Function” Cells 2022 https://doi.org/10.3390/cells11030368
Prathyush Pothukuchi , Ilenia Agliarulo, Marinella Pirozzi, Riccardo Rizzo, Domenico Russo, Gabriele Turacchio, Julian Nüchel, Jia-Shu Yang, Charlotte Gehin, Laura Capolupo, Maria Jose Hernandez‐Corbacho, Ansuman Biswas, Giovanna Vanacore, Nina Dathan, Takahiro Nitta, Petra Henklein, Mucund Thattai, Jin-Ichi Inokuchi, Victor W Hsu, Markus Plomann, Lina M Obeid, Yusuf A Hannun, Alberto Luini , Giovanni D’Angelo, Seetharaman Parashuraman “GRASP55 regulates intra-Golgi localization of glycosylation enzymes to control glycosphingolipid biosynthesis”. EMBO J 2021 PMID: 34516001
Prathyush Pothukuchi, Ilenia Agliarulo, Domenico Russo, Riccardo Rizzo, Francesco Russo, Seetharaman Parashuraman “Translation of genome to glycome: role of the Golgi apparatus” FEBS Letters 2019 PMID: 31330561
Ilenia Agliarulo, Danilo Swann Matassa, Maria Rosaria Amoroso, Francesca Maddalena, Lorenza Sisinni, Leandra Sepe, Maria Carla Ferrari, Diana Arzeni, Rosario Avolio, Giovanni Paolella, Matteo Landriscina, Franca Esposito “TRAP1 controls cell migration of cancer cells in metabolic stress conditions: Correlations with AKT/p70S6K pathways” Biochim Biophys Acta 2015 PMID: 26071104